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Tetrazole-bearing sulfonamide analogs as selective cyclooxygenases-2 (COX-2) inhibitors In 2023, combinatorial chemistry and computational studies helped researchers design xanthone moieties with high selectivity as potent COX-2 inhibitors (102) (Figure 13)

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Viral RNA Extraction and Real-Time Reverse-Transcription PCR Viral RNA extraction was performed from 50 l culture supernatant of SARS-CoV-2 infected Vero E6 and Calu-3 cells using the viral RNA kit (Macherey-Nagel) according to the instructions of the manufacturer

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