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Abstract Background To conduct a real-word-study-based cost-effectiveness analysis of a GLP-1 receptor agonist (GLP-1RA) versus insulin among type 2 diabetes patients requiring intensified injection therapy and a systematic review of cost-effectiveness studies of GLP-1RAs versus insulin

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Upset stomach or indigestion: Also referred to as dyspepsia, this includes general stomach discomfort, burning or a feeling of fullness during or after meals

Oriental Yeast, Tokyo, Japan) and water ad libitum at the Institute for Experimental Animals of Kanazawa University (Kanazawa, Japan)