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Three things to never do with a reconstituted blend: never refreeze it, never store it in the refrigerator door (where temperature swings on every door open), and never expose it to direct sunlight

Two estimands were employed: the trial product estimand, which evaluated treatment effects assuming perfect adherence to the assigned regimen, and the treatment policy estimand, which included all randomized participants regardless of adherence

The most commonly reported adverse effects are the GI symptoms associated with tirzepatide (nausea, reduced appetite) plus the mild headache occasionally seen with AOD 9604

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