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At all doses tested, tirzepatide achieved greater reductions in both HbA1c and body weight than semaglutide, providing some of the first head-to-head clinical data suggesting that dual incretin agonism may offer advantages over GLP-1 targeting alone

They can determine the cause, adjust the dosage, or find an alternative drug that works better for you

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They'll evaluate whether previous side effects have resolved or persist, as ongoing symptoms may contraindicate further dose increases