soul trial oral semaglutide cardiovascular outcomes results 2024 nejm 2025 Presented at ACC.25: Among participants Effects of Semaglutide on Heart

When dysbiosis sets in (often from antibiotics, processed foods, alcohol, mold exposure, chronic stress, or proton pump inhibitors), this estrogen handling becomes erratic, contributing to the very fluctuations that destabilize mast cells

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Ondansetron (48 mg as needed) is a serotonin 5-HT3 receptor antagonist that can be effective for GLP-1 agonist-related symptoms, though it may cause constipation, headache, and can prolong the QT interval in susceptible individuals