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There are three main ways: Methylmalonic acid (MMA) MMA is one of the most useful markers for detecting B12 deficiency, because B12 helps convert methylmalonyl-CoAone of the forms of MMAinto succinyl-CoA

For instance, some older studies suggest that people previously diagnosed with prostate or colorectal cancer who supplemented with more than 1,000 mcg of folic acid per day had a 1.76.4% higher risk of cancer recurrence ( Still, eating lots of folate-rich foods doesnt appear to increase cancer risk

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23 This can be incorporated as 0.4 g/kg/meal or about 20 g per meal depending on weight