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The largest of the trials lasted 12 months and included over 3000 participants

A meta-analysis of 27 randomised controlled trials found that berberine significantly reduced fasting blood glucose, HbA1c, triglycerides, total cholesterol, and LDL cholesterol

"We hypothesize that both weight loss and a direct anti-cancer effect and anti-inflammatory effect may be driving the associations observed in our study, Jones said

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