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Inflammatory cytokines cleave the N-terminal sequence of GSDMD, and this fragment binds to the cell membrane, forming pores and inducing cell rupture, ultimately leading to pyroptosis [95, 96]

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It was also observed that the mean difference in improvement (%) on VAS between baseline to 8th and 12th weeks over right cheek (TA) was found to be higher when compared with left glutathione [Table 3]

Lancet 342 : 193198 Schierbeek H, Te Braake F, Godin JP, Fay LB, van Goudoever JB 2007 Novel method for measurement of glutathione kinetics in neonates using liquid chromatography coupled to isotope ratio mass spectrometry