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At low to moderate concentrations (50200 M), CGA exerts protective effects, likely mediated by its antioxidant capacity

In individuals with overweight or obesity, treatment with semaglutide was associated with significant reductions in bodyweight, with a mean placebo-subtracted weight loss of 12.4% relative to placebo after 68 weeks reported in the STEP 1 trial

NAC (Sigma-Aldrich, A7250) was diluted in drinking water at a concentration of 30 mM, the pH was adjusted to 7.00 and it was provided to mice ad libitum