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That said, DEXA is certainly imperfect in splicing the details of this body composition change as adipose tissue includes plenty of lean mass. Additionally, the placebo group lost more lean mass (-1.83kg) than fat mass (1.37kg), which shows potential error. Nadolsky pointed out that rapid weight loss, in general, will reduce resting metabolic rate to some degree
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Unfolded protein response (UPR) is an adaptive response of the ER to maintain homeostasis (68)
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