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Nevertheless, the research and development of GLP-1R agonists provide new perspectives and strategies for the treatment of diabetes, obesity, and related complications

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Additionally, laboratory research has reported the following observations in controlled experimental systems: Furthermore, all reported observations are from preclinical laboratory studies or dietary supplementation research

While traditionally considered first-line therapy, current American Diabetes Association guidance emphasizes a person-centered approach to initial medication selection based on comorbidities, treatment goals, and patient preferences