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Once transported into cells, DHA undergoes a GSH-dependent, two-electron reduction to VitC, catalyzed by redox enzymes including glutaredoxin, omega-class glutathione transferases and protein-disulfide isomerase 10,11,12,13

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Additional parameters, including the presence or absence of refractory epilepsy, duration of disease progression, seizure frequency, temporal or extra-temporal localization for focal epilepsies, the presence or absence of abnormalities in brain magnetic resonance imaging, and details regarding the type of anti-seizure medications, were systematically determined