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For a product to be considered non-potentially hazardous, its water activity must be less than 0.86 aw or its pH less than 4.2 to ensure that no pathogenic bacteria will be able to grow on the product as it sits on the shelf

This mechanism gives rise to new unstable molecules, triggering a chain reaction that, if not stopped in time, ends up damaging cellular structures and metabolic processes

When temperature drops below freezing, ice crystals can form within the solution, rupturing the molecular bonds that make the medication work