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Preliminary evidence suggests supplementation with nutrients such as probiotics and prebiotics, omega-3 fatty acids from fish, vitamins D and K, and the minerals zinc and selenium may support kidney health as well

Tirzepatide is the first dual agonist which has been approved for chronic weight management, but numerous other dual and/or triple agonists (cagrisema, retatrutide, mazdutide and survodutide) are also in phase 3 trials as potential treatments for obesity and its metabolic complications

But indirect mechanisms

A high-fiber diet has been found to prevent gallstones in obese patients undergoing rapid weight loss (Sulaberidze 2014)