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10, 2025 A new study suggests popular GLP-1 drugs, like Ozempic and Zepbound, may not lower cancer risk as some had hoped

Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al

The cAMP/PKA pathway inhibits voltage-gated potassium channels that respond to depolarization, opens and allows K + efflux, repolarizing the cell and allowing increased calcium influx through voltage-dependent calcium channels, resulting in the exocytosis of insulin from -cells (115)

The work presented here, published in the journal Biomedicines , builds a bridge between laboratory bench and bedside by showing proof-of-concept that supplementing people with HIV specifically with a combination of glycine and N-acetylcysteine, which we call GlyNAC, as precursors of glutathione, a major antioxidant produced by the body, improves multiple deficits associated with premature aging, said Sekhar