10.3389/fphar.2020.00425 Summary Keywords acute kidney injury, chuan huang fang, chronic kidney disease, renal fibrosis, reduced glutathione, traditional Chinese medicine Citation Chen L, Ye Z, Wang D, Liu J, Wang Q, Wang C, Xu B and Gong X (2022) Chuan Huang Fang combining reduced glutathione in treating acute kidney injury (grades 12) on chronic kidney disease (stages 24): A multicenter randomized controlled clinical trial

Biological Effects of Hydrogen Antioxidant Effect Neutralization of ROS The disequilibrium between ROS and the antioxidant system causes oxidative stress which is considered as a common initial step for many pathological processes (Burton and Jauniaux, ), hydroxyl (OH), peroxyl (RO 2 ), alkoxyl (RO) radicals, and nitric oxide (NO), and they primarily come from mitochondrial respiration, NADH/NADPH oxidase, or xanthine oxidoreductase (Dan Dunn et al., 2 is a new type of reductant that can penetrate the cell membrane and neutralize particles that damage the body, OH and ONOO in cellular structure, and almost no effects of and H 2 O 2 which maintains physiological function and internal environment stability (Ohta, 2 + OH H 2 O + H followed by H + was considered as a potential mode of action (LeBaron et al., 2 could increase superoxide dismutase (SOD) activity and reduce lipid peroxide malondialdehyde (MDA) level in schistosomiasis-associated liver inflammation model

Broad-Spectrum Antioxidant Support Provides antioxidant support for whole-body cellular wellness
Maintaining GSH levels using therapies that do not deplete the bodys GSH (Sestili and Fimognari, 2020) would be the best choice