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Animal studies have shown that BSO significantly inhibits plaque formation in the arteries and reduces the expression of monocyte-derived macrophage growth, which is really important because those macrophages have been shown to take up oxidized LDL, then they become foam cells in the blood vessel wall and accelerate local inflammatory response that eventually leads to plaque formation

The implementation of such a program would require the determination and validation of standard molecular and microbiological methods, as well as the extended cost-utility analyses in collaboration with other professionals, including dietitians, microbiologists, and industry [88, 89]

Dashes are coloured according to the interaction types: Blue: hydrogen bond, red: water bridge, green: - interaction, magenta: hydrophobic interaction