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GLP-1R co-localisation with clathrin-coated pits (CCPs) with using TIRF microscopy INS-1 832/3 SNAP/FLAG-hGLP-1R WT or V229A cells were transfected with clathrin light chain (CLC)-GFP and plated onto poly-L-lysine-coated glass coverslips

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This increased availability of glutathione may contribute to a more pronounced skin-brightening effect

Medications: Sodium-glucose cotransporter-2 inhibitors 12 , DHEA 13 , dopamine agonists 14 and verapamil 15 can increase IGF-1 levels, while clomiphene citrate 16 , atorvastatin 17 and long-term somatostatin analogues can reduce IGF-1 18