Major PK Uncertainties: Translational Scaling : The PK parameters (especially clearance rates and effective doses) observed in small animals do not reliably scale up to humans
Freezing is generally not recommended unless specified by the peptides manufacturer
This indicates that the chimeras were well folded at the plasma membrane and that their respective basal transport activity of GSH is not impacted by the switch
17: Sikiric P, Boban Blagaic A, Krezic I, Zizek H, Kalogjera L, Smoday IM, Vukovic V, Oroz K, Chiddenton HM, Buric S, Antunovic M, Gojkovic S, Strbe S, Skocic M, Sikiric S, Milavic M, Beketic Oreskovic L, Kokot A, Koprivanac A, Dobric I, Sever M, Staresinic M, Batelja Vuletic L, Skrtic A, Seiwerth S