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The results of our study provide strong support for the use of both medicines in combination to reduce CV and kidney disease in people with type 2 diabetes. Neuen and colleagues conducted a meta-analysis of 12 trials that were part of SMART-C, a collection of trials that assess the effects of SGLT2 inhibitors on a primary clinical outcome for adults

Summary Multiple lines of evidence indicate that dysregulation of any of several components of the UPS, or mutations in genes that encode them, exacerbate AD progression and are deleterious to the recovery of function after SCI