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The results of this study provide additional support for a role of altered regulation of mitochondrial energy metabolism in the pathobiology of autism (Figure 5)

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Type 2 diabetes (34.80%) and weight loss (14.71%) emerged as the most predominant indications, while others accounted for 3.92%, and unknown or missing constituted 46.57% (Table 1)

For instance, elevated CXCL10 in vitiligo lesions not only attracts CD8 + T cells but also stimulates these cells to secrete additional IFN-, which further enhances CXCL10 expression, forming a self-amplifying inflammatory cycle