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Big Pharma is still piling in: Pfizer closed its 2023 $43B Seagen deal to expand its ADC platform, and PD-1 biosimilars are expected to arrive late-decade, expanding access rather than collapsing the category, as CRA Insights noted

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Enhancing insulin signaling in the hippocampus has shown promise in improving memory and cognition in AD models (Biessels and Reagan, 2015)

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