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10.3233/JAD-132471 34 KawadaH.KadorP

Bending and compressive stresses acting on the lumbar spine during lifting activities

The overall lower total organic content for the FA-conjugated material (30%) compared with the non-conjugated drug-loaded SBA-15 (50%) implies that conjugation reduced the amount of physically adsorbed (free) drug for example by replacing weakly adsorbed drug with covalently tethered folic-aciddrug species or by additional washing steps removing unbound drug