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Several side-chain modifications are also generated, making attaching to the target microRNA easier and providing protection from endogenous nucleases

The hydrolysis of progoitrin, found in cruciferous vegetables (see Figure 1 ), may yield a compound known as goitrin, which may interfere with thyroid hormone synthesis

Thyrocytes and thyroid fibroblasts pre-incubated with selenocompounds (selenomethionine and selenite) showed a dose-dependent increase in viability and a decrease in apoptosis indicators (caspase-3 activity, BAX mRNA levels) and an increase in the level of the inhibitor of apoptosis (BCL-2 mRNA) after incubation with H 2 O 2 , and also caused an increase in GPx activity (66)

Furthermore, dynamic postoperative monitoring of short-half-life proteins like prealbumin (PALB) can help assess the effectiveness of nutritional support and allow for timely adjustments to the nutritional plan (73)