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A 2025 retrospective analysis published in Ophthalmology Retina evaluated the incidence of DME among patients with type 2 diabetes who took various classes of medications

Its also shown promise in treating inflammatory bowel disorders like ulcers and Crohns disease

Only the antihyperglycemic effect of these drugs appears to be clearly related to the potentiation of incretins (i.e., GLP-1 and glucose-dependent insulinotropic polypeptide) [102, 103], possibly because such potentiation is confined to the gastrointestinal tract and may not be manifest systemically [63]

These are sequential phases of the same pathological process, and addressing only one while ignoring the other leaves the job half done