glp-1 drugs semaglutide Lower Risk of Death by 44% in Obesity and Autoimmune Disease New Guidelines on GLP-1 Drugs

doi: 10.1038/s41392-021-00687-0 42 YeungYTAzizFGuerrero-CastillaAArguellesS

The theoretical cancer concern and anecdotal effects, graded by source

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individuals with a personal history of cancer should discuss this explicitly with their specialist before use [8] [9] Retatrutide's side effect profile, based on published Phase 2 trial data (with Phase 3 trials ongoing), includes: Nausea, vomiting, and diarrhoea particularly during dose escalation Reduced appetite , which may lead to nutritional deficiencies if not monitored Increased heart rate Gallbladder-related complications , including cholelithiasis, consistent with the GLP-1 receptor agonist class When used together, these risks may compound