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Discussion 1) The results of this study completed by McCoy et al systematically evaluated the metabolic stability, BBB permeability, procognitive activity, and synaptogenic potential of Dihexa and other Nle-AngIV analogs, ultimately aiming to identify a therapeutic agent for dementia

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The ability of fecal microbiota transplantation to reduce inflammation, enhance intestinal barrier integrity through the production of SCFA, and rebalance immune function highlights its potential as an emerging treatment modality, particularly for ME/CFS [162]