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Clinical trials demonstrate that tirzepatide users lose 1522% of body weight over one year, with improvements in blood sugar control and cardiovascular risk markers

GLP-1 receptor agonists are prescribed for type 2 diabetes when other treatments are inadequate or unsuitable, according to NICE guidelines

When faced with such a prospect, a 24-h clear liquid diet does not seem to pose an equal risk or inconvenience. The bottom line is this: the most risk-mitigating approach based on the evidence would be to have patients fast for longer (ideally no solids for 24 hours and no liquids for perhaps longer than 2 hours)

Regular injections can help reduce the risk of neurological issues from long-term deficiency