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Description

Protein Cell 1 , 888897 (2010)

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Notably, this treatment increased the proportion of M1 macrophages expressing IL12 and IFN, leading to a more immunostimulatory tumor microenvironment ( Given the intratumoral heterogeneity of TAM polarization in ovarian cancer, a strategic combination of macrophage-targeted therapies, such as CSF1R and TREM2 inhibitors, with immunotherapies holds promise for improving clinical outcomes

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