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Laboratory Tests Sitagliptin The incidence of laboratory adverse reactions was similar in patients treated with sitagliptin and metformin immediate-release (7.6%) compared to patients treated with placebo and metformin (8.7%)

In the STEP trial [26], 8511 patients with hypertension aged 6080 years were randomized to the intensive treatment group targeting systolic blood pressure of 110130 mmHg and the standard treatment group targeting 130150 mmHg

QA-induced oxidative stress is further amplified by nitric oxide (NO) production via activation of NO synthase in both astrocytes and neurons [146]

doi: 10.1080/09540105.2013.837866 242 Brigelius-FlohRMllerCMenardJFlorianSSchmehlKWinglerK