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Saito T, Soma K, Kashisaka M, et al

Although it has been demonstrated that FOXO4-DRI has a strong preference for targeting senescent cells [24], because different organs or tissues have different drug sensitivities, the safety and tolerability of FOXO4- DRI must be considered

Unlike single-pathway compounds, retatrutide simultaneously activates three distinct receptor systems: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors [3]

For instance, a growth-hormone releasing peptide may increase IGF-1 and promote follicular development, while a repair peptide decreases local inflammation and promotes tissue remodeling, synergistically enhancing the implantation milieu