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28, 30 Caution is advised when prescribing colchicine to patients who are taking medicines that inhibit the CYP3A4 enzyme and/or P-glycoprotein, e.g

The unexpectedly profound weight loss observed in diabetes trials drove development of a higher-dose formulation Wegovy (up to 2.4 mg weekly) which received FDA approval in 2021 and EMA approval in 2023 specifically for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity