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Skin biopsy diagnostic histopathology and direct immunofluorescence is seen only in specific-LE lesions [see Discoid lupus erythematosus pathology] Blood tests full blood count, renal function test, inflammatory markers Serology including ANA, ENA are often negative in chronic CLE Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI) The Cutaneous Lupus Erythematosus Disease Area and Severity Index scores activity and damage in each of 12 anatomical locations

Based on the numbers here, the chart suggests that T3 is about 4x more potent than T4 as a thyroid medication

The risk-benefit of bupropion should be carefully assessed in pregnancy

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