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Conditions such as renal impairment (creatinine clearance under 60 mL per minute or clinically significant elevated serum creatinine), anemia, diabetes mellitus, electrolyte imbalance, vitamin B deficiency, and debilitating disease may enhance the occurrence of peripheral neuropathy

However, clinical studies on MCP and heavy metal poisoning are few, small, and biased

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J Womens Health (Larchmt) 19: 869-876