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Testosterone, Muscle Mass, and GLP-1 One concern men frequently raise when starting GLP-1 medications is muscle loss

Retatrutide is dosed at 2 mg once weekly for the first four weeks, then escalated every four weeks to a maintenance dose of 8 mg or 12 mg

Patients should seek medical attention if they experience severe or persistent gastrointestinal symptoms, signs of pancreatitis (severe abdominal pain radiating to the back), symptoms of thyroid tumors (neck mass, difficulty swallowing, persistent hoarseness), right upper quadrant pain, jaundice, reduced urine output, or unexplained hypoglycemia