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Justin Ryder and Veronica Johnson

Regular monitoring of B12 levels is typically recommended for those receiving ongoing treatment

Both Rybelsus and Farxiga can cause low blood sugar (hypoglycemia) when taken with insulin or insulin-releasing medications like sulfonylureas (e.g., glipizide and glyburide)

Whether retatrutide is ultimately studied directly against tirzepatide will depend on regulatory and commercial priorities, but the scientific value of such a trial is obvious, because only a controlled comparison in a single population under a single protocol can convert the current cross-trial impression into an actual finding