semaglutide and fasting Frontiers | Effects of semaglutide

If you take Zepbound (tirzepatide) or semaglutide and want to donate plasma, your eligibility may be affected by your medication status

You'll also have to consider where you'll be inserting the needle

doi: 10.1042/bsr20201273 251 WangWGuoPChenMChenDChengYHeL

Brand prices are list prices without insurance.* ## What Brand Retatrutide Will Likely Cost (Post-Approval) Based on [tirzepatide](/guides/tirzepatide-cost-price-guide-2026) (Zepbound at $1,059/month) and semaglutide (Wegovy at $1,349/month) pricing: | Scenario | Expected Monthly Cost | |----------|---------------------| | List price (no insurance) | $1,100-1,400 | | With commercial insurance | $25-500 (highly variable) | | With manufacturer savings card | Potentially $25-150 | The math is clear: [compounded retatrutide](/products/retatrutide-001) at $300-500/month is substantially cheaper than what the brand will cost