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Samples were analyzed on a timsTof Pro Mass Spectrometer (Bruker) as described previously (86)

Mller and Kuhn 2009)

Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials

If you are B12 deficient, correcting that deficiency whether through injections or oral supplements can significantly improve energy levels