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Description

Metabolic danger signals, uric acid and ATP, mediate inflammatory cross-talk between hepatocytes and immune cells in alcoholic liver disease

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They proposed a microfluidic platform constituted of three regions in which patient-derived B-ALL cells from different subtypes, together with primary commercial HUVECs, mesenchymal stem cells (MSC) and osteoblasts, were seeded for mimicking the human cytological and histological complexity of bone marrow ( Figures 5A-C )