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Side Effects: Common side effects include nausea, vomiting, diarrhoea, and decreased appetite

Protein carbonyl, a product of protein oxidative damage, has also been shown to be decreased by riboflavin administration in the rat models of diabetes (Reference Alam, Iqbal and Naseem31) , renal toxicity (Reference Alhazza, Hassan and Ebaid23) and anticancer drug-induced toxicities (Reference Naseem, Hassan and Alhazza28) , while its elevated level has been reported in riboflavin-deficient fishes (Reference Jiang, Chen and Liu33,Reference Chen, Feng and Jiang34)

The release of damage-associated molecular patterns by tumor cells undergoing ferroptosis also mediates antitumor immunity, and immune therapy can synergize with targeted therapy or radiotherapy through ferroptosis (153, 154)