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By estimating the correlations between amplitudes of individual GH secretory events and the average acyl-ghrelin concentration in the 60-minute interval preceding each GH burst, the ghrelin/GH association was more than 3-fold lower in the older group compared with the young adults, thus suggesting that with normal aging, endogenous acyl-ghrelin levels are less tightly linked to GH regulation

doi: 10.2337/diabetes.52.6.1449 [DOI] [PubMed] [Google Scholar] 163.Gerakis Y, Hetz C