In a recent study, our group examined the role of OATP2B1 in the intestinal absorption and tissue uptake of 3-hydroxy-3-methylglutaryl-CoenzymeA (HMG-CoA) reductase inhibitors (statins) (Varma et al
For proteome and ubiquitylome analysis of PR619-treated iNeurons, peptides were separated in trap/elute mode using a nanoAcquity MClass UPLC system (Waters Corporation, Milford, MA, USA) equipped with a trapping column (Waters nanoEase M/Z Symmetry C18, 5 m, 180 m 20 mm) and an analytical column (Waters nanoEase M/Z C18 HSS T3, 1.7 m, 75 m 250 mm)
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Urinary metabolomics analyses have further indicated that Huang-qi injections can modulate amino acid metabolism, the tricarboxylic acid (TCA) cycle, fatty acid metabolism, vitamin B6 metabolism, and purine metabolism in cisplatin-induced nephrotoxic rats (Liu et al., 2019)