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High NNMT expression is closely associated with glucose dysregulation: excessive NNMT activation disrupts nicotinamide metabolism, lowers NAD+ levels, impairs insulin signaling, reduces cellular glucose uptake and utilization, and promotes hyperglycemia and insulin resistance

However if you start to feel unwell, or are worried you may not have successfully delivered your biologic medicine, contact your IBD team immediately - they will advise what to do next.

4 In a follow-up study, researchers found that supplementing with vitamins B12 and B9 (folic acid) may increase the risk of colon cancer

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