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These may include: Nausea and stomach upset Diarrhea Constipation Injection site redness or swelling Itching Headache Dizziness Blood clots Swelling In rare cases, some people may experience an allergic reaction to vitamin B12, which can cause symptoms such as hives, difficulty breathing, and swelling of the face, lips, tongue, or throat

Within 48 hours after injection of 100 or 1000 mcg of vitamin B12, 50 to 98% of the injected dose may appear in the urine

B12 Injection Frequency for Deficiency Treatment When treating a vitamin B12 deficiency , how often you get B12 shots matters a lot