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Over time, the constant excretion of cortisol begins to fatigue the adrenal glands, and because the adrenals produce reserve stores of sex hormones, such as estrogen, progesterone, and testosterone, it may cause the body to steal the materials needed to make these sex hormones and convert them into more cortisol

Cord Med., 2010, 33(4):401-409Odabasoglu, Br

Mechanism of Action: How Melanotan Peptides Cause Skin Darkening Melanotan peptides act on specific skin cells and receptors to increase pigment production