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The predictive model found that clinical factors, including age, starting weight, and existing medical conditions, also contributed to the overall estimate

Estos resultados representan disminuciones de peso robustas y clnicamente relevantes en un periodo relativamente corto (13 semanas), superando muchas intervenciones farmacolgicas previas, lo cual es notable desde un punto de vista clnico y teraputico

Furthermore, protein carbonylation may be a secondary occurrence rather than a direct contributor to pathology, even though protein carbonyl concentrations are often higher than other biomarkers

These factors make maintaining a healthy weight difficult, or even impossible, without access to obesity treatment and interventions