Finasteride and other 5-alpha-reductase inhibitors, by inhibiting the conversion of testosterone to DHT, have the ability to cause abnormalities in the external genitalia of the male fetus
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Subsequently, PPD induced a high level of autophagy in EESCs, upregulated the expression of pro-apoptotic molecules, Bax/Bcl-2 antagonist/killer (Bak), and downregulated the expression of anti-apoptotic molecules (Bcl-2/Bcl-xL)
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