The SS peptide family comprises oligopeptides that specifically target mitochondria, thereby safeguarding their function by stabilizing the inner mitochondrial membrane and inhibiting the formation of mtROS [157]
Yet, after over a century of research, the penultimate biosynthetic step to anthocyanidins attributed to the action of leucoanthocyanidin dioxygenase has never been efficiently reconstituted outside plants, preventing the construction of heterologous cell factories
Increasing ATP availability, reducing reactive oxygen species (ROS) generation by mitochondrial complex I, inhibiting the mitochondrial permeability transition pore, and stimulating mitochondrial biogenesis, all seem to stabilize synaptic functions
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