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Indirectly, increased circulating IGF-1 could be a fingerprint of higher GH-IGF1 axis activity, and GH is able to modulate oligodendroglial cell survival and myelination in the CNS 27

Psoriatic arthritis and rheumatoid arthritis can be distinguished by the pattern of their symptoms and the presence or absence of certain blood markers

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Central to these interactions is the gut-thyroid axis, a bidirectional communication pathway that has emerged as a pivotal factor in elucidating the pathogenesis and progression of thyroid diseases (Figure 2)