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This results in dry, compacted stool that requires more straining to pass

**Pediatric Patients:** Dosage should be determined by a healthcare professional based on the child's age, weight, and clinical condition

La comparacin publicada frente a los ligandos endgenos mostr mayor potencia relativa sobre GIPR y menor potencia relativa sobre GLP-1R y GCGR

Going back to the IEL cells for a moment, in Crohns disease and ulcerative colitis (UC) these cells can start to attack the gut lining itself, this further creates a cytotoxic environment, which can further exacerbate IELs to produce pro-inflammatory proteins, this can lead to a compromised intestinal lining, along with alterations in the gut microbiome